Institutional Biosafety Committee (IBC)
Reviews, approves, and oversees research involving the use of biohazards
Introduction to the IBC
The Chi University Institutional Biosafety Committee (CU IBC) is established in accordance with NIH Guidelines to review and oversee all research and teaching activities involving biological agents. The committee ensures that all work conducted by faculty, staff, students, and visiting scientists is carried out with the highest standards of safety and responsibility.
Scope of Review
The IBC reviews research involving:
- Microorganisms and pathogens
- Recombinant or synthetic nucleic acid molecules
- Materials derived from humans or non-human primates
- Biological toxins
- Transgenic animals
Any such activities on Chi University property require IBC approval and oversight.
Mission & Values
The mission of the CU IBC is to protect public health, safeguard the environment, and ensure compliance with federal, state, and university regulations. The committee represents the interests of the surrounding community while upholding the highest ethical standards in research.
Containment & Facilities
The IBC sets and monitors containment levels for all biological research. Facilities used in research are reviewed for adequacy, safety measures, and compliance with biosafety standards to minimize risks to personnel and the public.
Training & Personnel
All individuals conducting research involving biological agents must demonstrate appropriate training and expertise. The IBC oversees training requirements to ensure that faculty, staff, and students are prepared to carry out their work safely and responsibly.
Procedures & Oversight
The IBC’s responsibilities include:
- Notifying principal investigators (PIs) of committee review and approval
- Establishing and, when necessary, modifying containment levels
- Implementing contingency plans for accidental spills or exposures
- Reviewing institutional procedures to ensure best practices
Compliance & Reporting
The IBC is committed to maintaining transparency and accountability. It reports to institutional officials within 30 days any:
- Substantial problems or violations of NIH Guidelines
- Significant research-related accidents or illnesses
This process ensures compliance and continuous improvement in biosafety practices.
Resources & Support
The IBC provides resources to support researchers, including:
- NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules
- University biosafety policies
- Training manuals and downloadable reference materials
Researchers may contact the IBC for guidance at any stage of their project.
Resources
IBC Members and Voting Power
Ex-officio, voting members:
- Chief EHS Officer
- Veterinarian
- Safety Officer
Ex-officio, alternate voting members:
- Biosafety Specialist
- Veterinarian
Ex-officio, Non-voting members:
- Provost
- Executive Vice President
- Director BRC
Investigator Responsibility
NIH Guidelines (Section IV-B-7)
The Principal Investigator is responsible for full compliance with the NIH Guidelines in the conduct of research involving recombinant or synthetic nucleic acid molecules, including ensuring that reporting requirements are fulfilled. The Principal Investigator is accountable for any reporting lapses.
Principal Investigators are responsible for ensuring IBC review of the following:
- Animal experiments requiring IBC approval with any of the above (prior to IACUC approval)
- Biological Toxins (Select Agent toxins below the permissible toxin amount)
- Human and Non-human Primate: blood, body fluids, tissues and primary or established cell lines
- Pathogens/Microorganisms: Risk Group 1 or higher
- Recombinant or Synthetic DNA work as defined by the NIH Guidelines
Trainings
To ensure proper safety, the IBC has provided the following training:
Policy and Plan
The following policies and plans are in place for the IBC:
IBC Mettings
The IBC meets at least once a year. Submissions must be received by close of business (5:00 p.m.) at least 10 days prior for consideration at the IBC meeting.
If you have any questions, please feel free to reach out to the committee chair Deng-Shan Shiau - dshiau@chiu.edu.